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Timothy Hall, Ph.D.

Timothy Hall, Ph.D.

Professor, Medical Physics

Department Affiliations

Medical Physics

Biomedical Engineering

Education

BA (Physics) University of Michigan-Flint

PhD (Medical Physics) University of Wisconsin-Madison

Positions

  • 1/2003-Present Professor, Dept of Medical Physics, University of Wisconsin-Madison

  • 6/1988-12/2002 Dept of Radiology, University of Kansas Medical Center (KUMC)

  • 1/1999-12/2002 Dept of Molecular and Integrative Physiology, KUMC

Research Interests

  • Acoustic scattering
  • Tissue elasticity
  • Breast imaging
  • Cervical assessment
  • Ultrasound phantom development

Our work involves developing quantitative methods in medical ultrasound. Within that effort are developments of experimental methods for estimating specific parameters (such as the acoustic backscatter coefficient (to quantify acoustic scattering on an absolute scale), effective scatterer size (to describe the tissue microstructure), and the nonlinear elastic modulus (to describe the tissue stiffness on an absolute scale)). Also within that effort are developments of test objects with known material properties (phantoms) that can be used to evaluate performance of these quantitative techniques, and performance descriptors that provide metrics to compare performance. The effort also involves integration of these methods into clinical imaging systems and tests in animal models, clinical trials in human subjects, and observer performance studies to test efficacy.

Our work involves a close collaboration with Siemens Medical Solutions Ultrasound Division and Siemens Corporate Research. That collaboration gives us access to their clinical imaging systems at the same level as their research and development engineers.

We are funded by the NIH to investigate breast tissue properties with ultrasound. A parallel effort investigates uterine cervix assessment associated with pre-term birth and predicting successful post-date inductions.

Awards and Honors

  • 1983 A.B. in Physics Summa Cum Laude, University of Michigan - Flint

  • 1983 Maize and Blue Scholar, University of Michigan

  • 1995 Best Paper of the Year, Ultrasound In Medicine and Biology

  • 2002 - Cum Laude Award, Radiological Society of North America

  • 2009 - Fellow of the American Institute of Ultrasound in Medicine

Memberships

  • American Association of Physicists in Medicine (AAPM)

  • Acoustical Society of America (ASA)

  • Institute of Electrical and Electronics Engineers (IEEE)

  • American Institute of Ultrasound in Medicine (AIUM)

Publications

  • Oberai AA, Gokhale NH, Goenezen S, Barbone PE, Hall TJ, Sommer AM, Jiang J. Linear and nonlinear elasticity imaging of soft tissue in vivo: demonstration of feasibility Physics Med Biol 54(5): 1191-1207, 2009.
  • Jiang J, Varghese T, Brace CL, Madsen EL, Hall TJ, Bharat S, Hobson MA, Zagzebski JA and Lee FT. Young's modulus reconstruction for radio-frequency ablation electrode-induced displacement fields: A feasibility study, IEEE Trans Med Imaging 28(8): 1325-1334, 2009.
  • Jiang J and Hall TJ, A generalized speckle tracking algorithm for ultrasonic strain imaging using dynamic programming, Ultrasound Med Biol 35(11):1863-1879, 2009.
  • Mitchell C, Hall TJ, Baker S, Burke M, Knauf L and Willey B, Can Hybrid Learning Theory Be Utilized To Teach Working Sonographers Breast Elastography? accepted for publication in Journal of Diagnostic Medical Sonography June 2009.
  • Jiang J, Varghese T, Chen Q, Hall TJ and Zagzebski JA. Finite element analysis of tissue deformation with a radiofrequency ablation electrode for strain imaging, accepted for publication in (UFFC) August 2009.
  • King MR, Anderson JJ, Herd MT, Ma D, Haak A, Madsen EL, Wirtzfeld L, Zagzebski JA, Oelze ML, Hall TJ and O'Brien WD Jr., Ultrasonic backscatter coefficient estimates from agar spheres in agar phantoms, J Acoust Soc Am 128(2): 903-908, 2010.
  • Jiang J, Brace C, Andreano A DeWall RJ, Rubert N, Fisher TG, Varghese T and Hall TJ. Ultrasound- based relative elastic modulus imaging for visualizing thermal ablation zones in a porcine model. Phys med Biol 55(8):2281-306, 2010.
  • Fisher TG, Hall TJ, Panda S, Richards MS, Barbone PE, Jiang J, Resnick J, Barnes S. Volumetric Elasticity Imaging with a 2-D CMUT Array, Ultrasound Med Biol 36(6):978-90, 2010.
  • Pavan TZ, Madsen EL, Frank GR, Carneiro AAO, and Hall TJ. Nonlinear elastic behavior of phantom materials for elastography, Phys Med Biol, 7;55(9):2679-92, 2010.
  • Anderson JJ, Herd MT, King MR, Haak A, Hafez ZT, Song J, Oelze ML, Madsen EL, Zagzebski JA,
  • O'Brien WD Jr. and Hall TJ, Interlaboratory comparison of backscatter coefficient estimates for tissue-mimicking phantoms, Ultrasonic Imaging 32:159-171, 2010.
  • Feltovich H, Nam K and Hall TJ. Quantitative ultrasound assessment of cervical microstructure, Ultrasonic Imaging 32:33-47, 2010.
  • Wirtzfeld LA,Ghoshal G, Hafez ZT, Nam K, Labyed Y, Anderson JJ, Herd MT, Haak A, Miller RJ, Sarwate S, Zagzebski JA, Bigelow TA, Hall TJ, Oelze ML and O'Brien WD Jr. Cross- imaging platform comparison of ultrasonic backscatter coefficient measurements of live rat fibroadenomas J Ultrasound Med 29(7):1117-2, 2010.
  • Xu H, Rao M, Varghese T, Sommer A, Baker S, Hall TJ, Sisney GA, Burnside ES. Axial-shear strain imaging for differentiating benign and malignant breast masses. Ultrasound Med Biol 6(11):1813-24, 2010.
  • Dapore AJ, King MR, Harter J, Sarwate1 S, Oelze ML, Zagzebski JA, Do MN, Hall TJ, O'Brien WD, Jr. Analysis of human fibroadenomas using three-dimensional impedance maps. IEEE Trans Med Imaging 30(6): 1206-1213, 2011.
  • Herd MT, Hall TJ, Jiang J and Zagzebski JA. Improving the statistics of quantitative ultrasound techniques with deformation compounding accepted for publication in Ultrasound Med Biol February 2010.
  • Jiang j and Hall TJ. A fast hybrid algorithm combining regularized motion tracking and predictive search for reducing the occurrence of large displacement errors IEEE Trans Ultrason Ferroelec Freq Contr 58(4):730-736, 2011.
  • Hall TJ, Barbone P, Oberai AA, Jiang J, Dord JF, Goenezen S, Fisher TG. Recent results in nonlinear strain and modulus imaging. accepted for publication in Current Medical Imaging Reviews.
  • Sarvazyan A, Hall TJ, Urban MW, Fatemi M, Aglyamov SR, Garra BS. An overview of elastography - An emerging branch of medical imaging. accepted for publication in Current Medical Imaging Reviews.
  • Nam K, Zagzebski JA and Hall TJ. Simultaneous backscatter and attenuation estimation using a least squares method with constraints. accepted for publication in Ultrasound Med Biol.

Patents

  • Method and Apparatus for Motion Estimation within Biological Tissue by Chaturvedi P, Hall TJ, and Insana MF, US Patent 6,277,074, Aug 21, 2001.
  • Ultrasound Elasticity Imaging by Zhu Y and Hall TJ US Patent 6,508,768, Sept 17, 2001.
  • Automated Ultrasonic Elasticity Imaging Formation with Quality Measure by Jiang J, Hall TJ and Sommer AM International Patent No. WO/2007/001527 (US application 20060285731).
  • Ultrasonic Strain Imaging Device and Method Providing Parallel Displacement Processing by Jiang J and Hall TJ International Patent No. WO/2007/111765 (US application 20070234806).
  • A Novel Ultrasound Speckle Tracking Method for Tracking Non-Axial Motion in Elasticity Imaging by Jiang J and Hall TJ (disclosure accepted by WARF 20.Jul.2007)
  • Speed of sound measurement by array transducers through texture orientation of pre-beam formed echo data by Jihad Hassan Al-Sadah, Zagzebski JA, Hall TJ (disclosure accepted by WARF Nov.2007)
  • Ultrasonic strain imaging device with selectable cost function by Jiang J and Hall TJ (disclosure accepted by WARF Nov.2007)
  • A Method for Producing Highly Constrained Ultrasound Images by Zagzebski JA, Mistretta CA and Hall TJ (disclosure accepted by WARF Nov.2007)
  • Noninvasive ultrasonic methods of cervical microstructure assessment by Feltovich HM and Hall TJ (disclosure accepted by WARF May 2008)


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