Weibo Cai

Publications

Selected publications:

1. Liu Z,* Cai W,* He L, Nakayama N, Chen K, Sun X, Chen X, Dai H. In-vivo biodistribution and highly efficient tumor targeting of carbon nanotubes in mice. Nature Nanotechnology, 2007, 2, 47-52. (Cited > 1100 times)
2. Zhang Y, Jeon M, Rich LJ, Hong H, Geng J, Zhang Y, Shi S, Barnhart TE, Alexandridis P, Huizinga JD, Seshadri M, Cai W,* Kim C,* Lovell JF.* Non-invasive multimodal functional imaging of the intestine with frozen micellar naphthalocyanines. Nature Nanotechnology, 2014, 9, 631-638.
3. Jiang D, Ge Z, Im H-J, England CG, Ni D, Hou J, Zhang L, Kutyreff CJ, Yan Y, Liu Y, Cho SY, Engle JW, Shi J, Huang P, Fan C, Yan H, Cai W. DNA origami nanostructures can exhibit preferential renal uptake and alleviate acute kidney injury. Nature Biomedical Engineering, 2018, 2, 865-877.
4. Ni D, Jiang D, Ehlerding EB, Huang P, Cai W. Radiolabeling silica-based nanoparticles via coordination chemistry: basic principles, strategies, and applications. Accounts of Chemical Research, 2018, 51, 778-788.
5. Luo H, Hernandez R, Hong H, Graves SA, Yang Y, England CG, Theuer CP, Nickles RJ, Cai W. Noninvasive brain cancer imaging with a bispecific antibody fragment, generated via click chemistry. Proceedings of the National Academy of Sciences of the United States of America. 2015, 112, 12806-12811. (PMCID: PMC4611632)
6. Yang Y, Hernandez R, Rao J, Yin L, Qu Y, Wu J, England CG, Graves SA, Lewis CM, Wang P, Meyerand ME, Nickles RJ, Bian XW, Cai W. Targeting CD146 with a 64Cu-labeled antibody enables in vivo immunoPET imaging of high-grade gliomas. Proceedings of the National Academy of Sciences of the United States of America, 2015, 112, E6525-E6534.
7. Cai W, Chen X. Preparation of peptide-conjugated quantum dots for tumor vasculature-targeted imaging. Nature Protocols, 2008, 3, 89-96.
8. Chen F, Ellison PA, Lewis CM, Hong H, Zhang Y, Shi S, Hernandez R, Meyerand ME, Barnhart TE, Cai W. Chelator-free synthesis of a dual-modality PET/MRI agent. Angewandte Chemie International Edition, 2013, 52, 13319-13323. (PMCID: PMC3855680)
9. Shi S, Xu C, Yang K, Goel S, Valdovinos HF, Luo H, Ehlerding EB, England CG, Cheng L, Chen F, Nickles RJ, Liu Z, Cai W. Chelator-free radiolabeling of nanographene: Breaking the stereotype of chelation. Angewandte Chemie International Edition, 2017, 56, 2889-2892.
10. Yu B, Wei H, He Q, Ferreira CA, Kutyreff CJ, Ni D, Rosenkrans ZT, Cheng L, Yu F, Engle JW, Lan X, Cai W. Efficient uptake of 177Lu-porphyrin-PEG nanocomplexes by tumor mitochondria for multimodal-imaging-guided combination therapy. Angewandte Chemie International Edition, 2018, 57, 218-222. (PMCID: PMC5745268)
11. Chakravarty R, Valdovinos HF, Chen F, Lewis CM, Ellison PA, Luo H, Meyerand ME, Nickles RJ, Cai W. Intrinsically germanium-69-labeled iron oxide nanoparticle: synthesis and in-vivo dual-modality PET/MR imaging. Advanced Materials, 2014, 26, 5119-5123.
12. Goel S, Ferreira CA, Chen F, Ellison PA, Siamof CM, Barnhart TE, Cai W. Activatable hybrid nanotheranostics for tetramodal imaging and synergistic photothermal/photodynamic therapy. Advanced Materials, 2018, 30, 1704367. (PMCID: PMC5805572)
13. Ni D, Ferreira CA, Barnhart TE, Quach V, Yu B, Jiang D, Wei W, Liu H, Engle JW, Hu P, Cai W. Magnetic targeting of nanotheranostics enhances Cerenkov radiation-induced photodynamic therapy. Journal of the American Chemical Society, 2018, 140, 14971-14979.
14. Cai W, Shin DW, Chen K, Gheysens O, Cao Q, Wang SX, Gambhir SS, Chen X. Peptide-labeled near-infrared quantum dots for imaging tumor vasculature in living subjects. Nano Letters, 2006, 6, 669-676. (Cited > 1000 times)
15. Ni D, Jiang D, Valdovinos HF, Ehlerding EB, Yu B, Barnhart TE, Huang P, Cai W. Bioresponsive polyoxometalate cluster for redox-activated photoacoustic imaging-guided photothermal cancer therapy. Nano Letters, 2017, 17, 3282-3289. (PMCID: PMC5495651)
16. Cai W, Wu Y, Chen K, Cao Q, Tice DA, Chen X. In vitro and in vivo characterization of 64Cu-labeled AbegrinTM, a humanized monoclonal antibody against integrin αvβ3. Cancer Research, 2006, 66, 9673-9681.
17. Luo H, England CG, Shi S, Graves SA, Hernandez R, Liu B, Theuer CP, Wong HC, Nickles RJ, Cai W. Dual targeting of tissue factor and CD105 for preclinical PET imaging of pancreatic cancer. Clinical Cancer Research, 2016, 22, 3821-3830. (PMCID: PMC4970931)
18. Hernandez R, Graves SA, Gregg T, VanDeusen HR, Fenske RJ, Wienkes HN, England CG, Valdovinos HF, Jeffery JJ, Barnhart TE, Severin GW, Nickles RJ, Kimple ME, Merrins MJ, Cai W. Radiomanganese PET detects changes in functional β-cell mass in mouse models of diabetes. Diabetes, 2017, 66, 2163-2174. (PMCID: PMC5521871)
19. Ehlerding EB, Sun L, Lan X, Zeng D, Cai W. Dual-targeted molecular imaging of cancer. Journal of Nuclear Medicine, 2018, 59, 390-395.
20. Hong H, Severin GW, Yang Y, Engle JW, Zhang Y, Barnhart TE, Liu G, Leigh BR, Nickles RJ, Cai W. Positron emission tomography imaging of CD105 expression with 89Zr-Df-TRC105. European Journal of Nuclear Medicine and Molecular Imaging, 2012, 39, 138-148. (PMCID: PMC3228902) (EANM Springer Prize for Best Basic Science Paper)